Clinical Trials Research

AIROPLANE: Air or Oxygen for Preterm Infants: An Embedded Trial

What is it?

The AIROPLANE Trial compares two different oxygen concentrations to help support a baby's breathing in the first few minutes after birth. The trial assesses whether either approach leads to babies having less need for later breathing support, oxygen treatment or less time in hospital.

The hospitals taking part in the AIROPLANE Trial will be allocated to use an initial oxygen concentration of either 21% or 30% for a period of approximately 12 months. After this time, the hospital will then change to using the alternative oxygen concentration for a similar period of time.

Safety measures have been built into the study design to ensure that every AIROPLANE baby always receives a safe level of oxygen. Should additional care be needed at any time this will always be provided immediately.

Who do I speak to?

This trial has been initiated out of Murdoch Children's Research Institute and you can contact the AIROPLANE trial team AIROPLANE.Trial@mcri.edu.au 

Our local Principal Investigator is Dr Mark Norden, Director of Women's and Childrens Services.

Where do I find more information?

See the AIROPLANE Trial Website

Using disinvestment to investigate the effectiveness of mobilisation alarms in a stepped-wedge randomised trial design in tertiary hospitals (Control site)

What is it?

The aim of the study is examine the use of mobilisation alarms as a strategy to prevent falls in hospitals in Australia, with a view to removing the falls alarms from some of the study sites and understand the impact of this. Albury Wodonga Health is in the control arm of this study, meaning no change to practice is currently happening regarding falls alarms, instead we are auditing their use.

Who do I speak to?

This study has been initiated out of the School of Primary and Allied Health Care & National Centre for Healthy Ageing, Monash University and is funded through the National Health and Medical Research Council, Australian Government. Grant number: APP1186185.

Our local Principal Investigator is Dr Marina van Leeuwen, UNSW and AWH Research Coordinator.

Where do I find more information?

See this publication on the study:

Haines, T. P., Botti, M., Brusco, N., O'Brien, L., Redley, B., Bowles, K. A., Hutchinson, A., Mitchell, D., Jellett, J., Steen, K., Boyd, L., Webb-St Mart, M., Raymond, M., Hunter, P., Russo, P., Bonnici, R., Pu, D., Sevenhuysen, S., Davies, V., & Shorr, R. (2021). Disinvestment in the presence of uncertainty: Description of a novel, multi-group, disinvestment trial design and protocol for an application to reduce or cease use of mobilisation alarms for preventing falls in hospitals. PloS one, 16(12), e0261793. https://doi.org/10.1371/journal.pone.0261793

Identifying and addressing barriers and enablers to implementing best-practice cardiac rehabilitation: the Quality Improvement in Cardiac Rehabilitation (QUICR) Cluster-Randomised Controlled Trial 

What is it?

The purpose is to investigate whether cardiac rehabilitation program sites participating in a data-driven collaborative quality improvement intervention (QUality Improvement in Cardiac Rehabilitation (QUICR)) delivered over 12 months: 1) increase cardiac rehabilitation program completion, 2) reduce unplanned hospitalisations and associated length of stay and ED presentations, 3) improve the proportion of patients receiving guideline-indicated cardiac rehabilitation using national and international benchmarks, and 4) improve patient outcomes at program completion compared to a no-intervention control group. 

Who do I speak to?

This study has been approved by the Northern Sydney Local Health District HREC (2023/ETH01093). Questions about the project can be directed to NSLHD-Research@health.nsw.gov.au

The local principal investigator is Ivy Biacsi, Cardiac Rehabilitation Coordinator, AWH

Where do I find more information?

Monash University projects